Crosslinkers & Reagents

HAWORKS offers a comprehensive portfolio of high-purity crosslinkers, photoinitiators, and bio-orthogonal coupling reagents designed for reliable, reproducible hydrogel network formation, 3D bioprinting, and biomaterial engineering.

Whether you are designing light-curable bioinks, spontaneous chemical networks (such as thiol-ene or disulfide bridging), or stimuli-responsive delivery systems, our reagents ensure precise control over gelation kinetics, crosslinking density, and mechanical stiffness.

Key Product Categories

• Photoinitiators & Light-Curing Agents:

  High-efficiency, biocompatible photoinitiators (including LAP and Irgacure 2959) optimized for rapid crosslinking under UV and visible light (365 nm – 405 nm) with high cell viability for photocrosslinkable polymers (HAMA, GelMA, Methacrylated Alginate/Dextran).

• Thiol-Based & Chemical Crosslinkers:

  Bifunctional and multi-arm linkers (such as multi-arm PEG-SH, PEG-DA, DVS, and thiolated crosslinkers) facilitating spontaneous crosslinking via Michael addition, disulfide bridging, or Schiff base reactions under mild physiological conditions.

• Bio-Orthogonal & Click Chemistry Reagents:

  Catalyst-free, rapid-curing click chemistry pairs (Azide/DBCO, Tetrazine/TCO, Thiol-Maleimide) ideal for encapsulated cell studies and in vivo translational models.

• Biopolymer Coupling & Activation Reagents:

  Homobifunctional and heterobifunctional crosslinkers (NHS esters, maleimides, hydrazides, EDC/NHS) for covalent biomolecule tethering and peptide conjugation.